Oh, these guys made the Max Payne series? I have no further doubt they know what they are doing. In Max Payne, players will remember encountering several different enemies with that crazy drug in them. most of them are zombie like, almost, standing up and shooting and forget about the damage they take. But some of them ramble, and one of them was a boss making sacrifices. He ranted continually.
Later, Max is injected with the drug himself, and goes through this weird dream sequence. At one point, you pick up a ringing phone, and though Max narrates he doesn't understand what is being said, you can clearly hear Max himself rambling on continuously.
That sequence was extremely freaky. The idea that, while you're in here, running around while blood flakes drift from the sky, you're actually out there, running around and doing things; the idea that you are not in control, is unsettling.
I think this is kinda what makes the horror genre best in video games. You do not have control, you do not get a say in the matter. Dead Space and Left 4 Dead are not really horror; you can control the situation to a large extent. But picture playing Left 4 Dead with about half the zombies, a character with a broken leg, blurry vision if you are "hit" (because you lose your glasses or something). You are not in control; you can't just run, and you can't really kill completely accurately. That would be much more unsettling.
