Researchers Spot And Manipulate Zombie Gene In Caterpillars

vansau

Mortician of Love
May 25, 2010
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Researchers Spot And Manipulate Zombie Gene In Caterpillars



You just know that this is the start of the experiment that winds up causing the zombie caterpillar apocalypse.

Did you know there's actually a virus that controls caterpillars as it kills them? It's true: Out in the wild, there's a baculovirus that controls gypsy moth populations by causing them to spread the infection even as it's liquifying their insides. Not only that, but a group of researchers recently identified the gene in the virus that dictates the insects' actions and figured out how to deactivate it.

Gypsy moth caterpillars spend their nights climbing into trees so they can eat leaves, but they return to forest floors during the day so they can avoid predators that hang out amongst the branches. However, a baculovirus actually causes the little guys to climb up into trees during the daytime, which helps with the virus's reproductive cycle.

Infected caterpillars, meanwhile, are also having their interior bits eaten up by the virus. Once they're up in the treetops, they die and are liquified, thereby dribbling all over the foliage below; any other caterpillars that come into contact with the remains are then infected and the cycle starts all over again.

Entomologist Kelli Hoover theorized that the caterpillars' behavior might've had a genetic connection:

The gene egt codes for an enzyme, EGT, that inactivates the hormone in these caterpillars that triggers molting. Because caterpillars usually descend from the treetops to molt on the ground, the researchers reasoned that the bugs were staying high in the trees to die because EGT was blocking the molting hormone.

Hoover and her team infected a test batch of caterpillars with two versions of the virus: one with the egt gene and one without. While the caterpillars still died gooey deaths, the egt-free ones were sitting on the bottom of their containers. Those infected with unmodified ("wild") versions of the virus were firmly ensconced at the top of their containers.

Now that the researchers have figured out how to tweak the virus, it's only a matter of time before they figure out how to make it bring its victims back from the dead after they've expired. After that, we can all look forward to living through our very own George Romero movie.

... Right?

Source: <a href=http://www.sciencemag.org/content/333/6048/1401>Science via <a href=http://io9.com/5837426/scientists-identify-gene-responsible-for-zombie-caterpillars>io9

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Art Axiv

Cultural Code-Switcher
Dec 25, 2008
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Well... pic related is related.. but it isn't really zombie, because they kinda die right?
 

The Funslinger

Corporate Splooge
Sep 12, 2010
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To quote Fry: "is this going to be one of those experiments that crosses a line man was not meant to cross?"
 

Joshimodo

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Sep 13, 2008
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Art Axiv said:
Well... pic related is related.. but it isn't really zombie, because they kinda die right?
I think it's more related to the mind-controlling virus that wants to spread the infection rather than the reanimated dead part of zombie mythos.
 

Xan Krieger

Completely insane
Feb 11, 2009
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Dear researchers: Please quit messing with nature before you kill us all.
Sincerely, everyone who wants to live.
 

Vigormortis

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Nov 21, 2007
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Honestly, this isn't surprising to me. This sort of thing has existed for about as long as life itself. For example, there is a fungus that, once it infects an ant, will work it's way into the ants brain and nervous system. As soon as it is entrenched within, it will cause the ant to seek out other ants and cause the ant to have an urge to climb to a high point near by. Once in position, a stalk of the fungus will grow out of the back of the ants head and release a spray of spores that rain down on any other ants in the area. Then, the cycle repeats.

This fungus has been around for so long that many of the ant colonies that are confronted with it actually know how to deal with it. They'll often send another ant to carry the infected one to a location far from the colony. (which often ends up being a suicidal "mission")

However, I will say that I'm glad those researchers were able to identify and single out the aspect of the virus that activates the gene that causes that behavior in the gypsy months. Discoveries like this are a big step towards figuring out how to, say, shut off cancer cells or cure a plethora of other genetic diseases.

GO SCIENCE!!
 

CGAdam

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Nov 20, 2009
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Aren't Gypsy moths still considered an environmental blight? Wouldn't making them all commit bacterially induced suicide be a good thing? Also, doesn't that sound like the morally unsound move that would start said apocalypse?
 

Plumerou

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Mar 7, 2011
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OK GUYS, time to build safe houses scattered in random locations around the city, we will need ammunition, medkits, pain killers and some markers to make random writings in the walls, we must make sure to have them all prepared before the first 2 weeks of infection :X
 

Rednog

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Nov 3, 2008
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Xan Krieger said:
Dear researchers: Please quit messing with nature before you kill us all.
Sincerely, everyone who wants to live.
You know that this thing exists in nature, it isn't anything that scientists cooked up in a lab, right?
Also they figured out how to disable the actions it causes the victims to do, this is a positive thing.
 

TitanAtlas

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Oct 14, 2010
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Well... this is going to run well....

Like nothing bad could happen... am i right? *grabs fire axe* ehrm... just in case...
 

brodie21

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Apr 6, 2009
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im going to go buy a bolt action rifle, a battle ready katana, and a shaolin spade to put in the new hideout i am building in the wilderness. wake me when the zombies get here
 

Fiz_The_Toaster

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It would appear I'm going to have to get a shotgun a lot sooner than I expected, but until then I have to make sure my katanas are all sharpened. I'll be damned if I'm caught off guard!
 

Zeraki

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Feb 9, 2009
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Well I was enjoying my ice cream until I started reading this article. I got up to the part with the liquifying before I had to stop.

-several minutes later, after reading the article-

So, it looks like it is time to go plant some sunflowers on my lawn!
 

marurder

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Jul 26, 2009
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So if some freakish accident happens and people contract a mutant version of this virus..


LEEEAAVVVEESSSS......

(the plants are REALLY screwed now)
 

Baresark

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Dec 19, 2010
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Rednog said:
Xan Krieger said:
Dear researchers: Please quit messing with nature before you kill us all.
Sincerely, everyone who wants to live.
You know that this thing exists in nature, it isn't anything that scientists cooked up in a lab, right?
Also they figured out how to disable the actions it causes the victims to do, this is a positive thing.
Actually, this is linked to controlling the gypsy moth population, so blocking it would not benefit them or people. In New Mexico, they try to help control it by burning the fields at the beginning of every season. So, this hurts, not helps.

GO SCIENCE
 

soren7550

Overly Proud New Yorker
Dec 18, 2008
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Great, now I have to worry about zombie caterpillars. Thanks Escapist, you've just added another oddity to this nut bag.