Well, holy shit. I've been necro'd. Not that I mind, since I wanted this one answered.
For all those that know the howl/roar: Thank you for backing me up.
For all those that never heard it: Keep listening!
You see, I remembered where it was that I heard the howl. It was in Fallout 3, in Raven Rock. (Which is where I found a giant armored man in a tube, BTW.) You see, Eden's zorched and the place is going up, but there's a cage in the hallway... I opened it up and...hello, Deathclaw. It was a disoriented remote control one who was 'off the leash'. I got...right out of his way as he exited, stretched, let off a howl, and chased after a couple soldiers.
Thank you for confirming quite possibly one of the most evil fucking howls around.