I'd say that the best moral choice system was the one seen in "Heavy Rain" (SPOILERS!)At the moment when I was at the end of the trial where you have to kill a person, I really had to think. Because there was no answer to that question, would you end a human life which is worth as much as any other to save your son? When I finally made up my mind and shot him, I had to look away from the screen because I felt like horrendous monster. That's the kind of moral choice I like, the kind that actually makes feel bad for taking the "evil" alternative.
@mjc0961: "inFAMOUS" is one of my favorite games of all time, the thing that didn't work in it was mainly that you were required to choose a path and stick to it, there were moments where I really wondered (again SPOILERS!) if I should save Trish from her dead, or rather save the doctors, which would in turn, save a lot of lives, or at the time where I found a guy that wouldn't let me through a gate until I reunited him with his wife, should I tell him that his wife is dead, and let him live in suffering, or should I put him out of his misery. And while, yes some choices ended up in the same thing, they felt meaningful at the time, and I hope these two issues are solved by the time "inFAMOUS 2" comes out (I´m so preordering the shit out of that game!)