MY consoles that are currently hooked up get cleaned every week with my regular dusting. I give them a good cleaning about every couple of months with air can and alcohol. Controllers OTOH I clean with alcohol daily when using them. Though usually the controllers wind up needing surgery due to crappy joysticks anyhow and when I take them apart to repair them they get a deep cleaning and come out looking like new. If the console sits there for years in use, every once in a while I take the case off and clean the insides as well because you can't really get inside the vent areas really well otherwise.
The rest of my ridiculous amount of consoles are deep cleaned, inside and out before stored in with silica packs to keep the moisture out so they come out looking like new when I decide to get them out of the box. You should save those silica moisture absorbing packs from like new shoe boxes and in medicine jars and use them when storing your electronics. If you are storing old retro cartridge consoles and games, it is always a good idea to put large sealed silica packs in the cartridge slot itself to keep the metal connectors from corroding inside there. They come out looking like new no matter how long I have them in there when I do that. Be sure NOT to put too small ones down there and get them stuck though because it is a pain to get them back out again! ( Did that once HAHA!). Use the small ones instead in the cartridges themselves where the metal connectors are so they do not corrode either.
Moisture ALWAYS seems to find a way into storage boxes even when you do not see any and it think it not possible, also sealed up plastic is the worst with trapping it in there and causing corrosion ( like plastic storage boxes) so don't ever store electronics in there without something to absorb moisture or they will be useless when you take them out later.
I have a habit of taking everything I own apart and working on it so I may go a bit overboard with my cleaning. It is just when you think something is clean, then you open it and go "OMG how did cat hair get inside there and did my brother SERIOUSLY get the chips he was eating INSIDE MY CONSOLE while he was here? WTF? I should go trash his house and see how HE likes it!". Often you do not realize how dirty it really is until you open it. XD