Don't get me wrong, I like anime as much as the next guy, but it would probably be living hell if anime tropes came to life. Especially if it were an ecchi/harem anime. Imagine getting beaten and battered every time the plot(fate in this case I guess) decides to show you their panties or have you walk in on them naked when they are in a room that you should be able to walk into without having to worry about encountering naked people, and then ending up in the hospital after receiving a severe concussion from whatever blunt object she decided to beat you with. And when you get out of the hospital, no one has any sympathy, because it's your fault apparently. And you'd probably have a case of main character stupidity, and be unable to use common sense to avoid some of the more avoidable beatings.
I pretty much stopped watching those kind of anime entirely because they piss me off way too much. Anyways, as for other anime cliches. I'd probably go deaf from the screeching cutesy anime voices, or at least bleed from my ears. I would suffer from severe blood loss due to inevitable nose bleeds. 25 percent of the liquid would be drained out of my face for a giant plewd to form whenever something strange or embarrassing happens. Those are the main things I can think of.