Have you tried Battlestar Galactica? (I'm talking about the the game). It's web browser based but graphics are on par with EVE's. I played only the tutorial but it seemed entertaining for the Spacer type. I myself couldn't cope with EVE's and X3's controls and the "you are the ship" game mechanics.
Something that blended ship design and construction with being able to watch and command every little thing (ship, crew, buying, selling, exploring, etc.) from a ship-commander viewpoint (first or third person) would be awesome. Upgrading the ship, making decisions and fighting wars or something. Mass Effect meets Deus Ex.