The production values are surprisingly well done, I'm impressed. I love how it constantly switches back and forth between reality and the fantasy (potential future episode? Hmmm, doubt it, but could be interesting).
However, I do have some of the same criticisms that others have said;
-I don't play D&D, and I'm sure many others don't (and do). D&D references are all well and good, but try not to alienate those who aren't "in" on the joke.
-Try to avoid making the D&D players blatant stereotypes (even though, in a way, D&D kind of relies on preset character models). They don't have to be fully 3-dimensional characters, but from what I've seen there's just the "creepy guy" goblin, "the fat one" who of course goes for Sci-fi, "the girl" who seems to go too quickly into adoring the men, "the skinny nerd" who's just, well, the skinny nerd, and "the uptight buzzkill" GM.
-Especially be careful with the female character, please don't make her just eye-candy or a pure ditz. I'm sure there are many thing you can do with the "OMG, a GIRL!" scenario, just be careful with it.
-As someone stated earlier, these guys do come off as a bit too wacky with each other. It's difficult to see why they'd gather together for a D&D game. That's something this could easily delve into, why do people play D&D games? It doesn't have to be dramatic or anything, keep the comedy if you can think of something. But a D&D game (to my knowledge) requires cooperation with the group to be successful, and this just comes off as a bunch of people living out their own fantasies instead of a group of friends joining in for an adventure.
I say these criticisms in the utmost sincerity. So far I feel that this is coming off as a strong new series. This series is kicking to a good start, but of course it could be better in many areas. This is an intriguing idea, and it'd be great to have another series to look forward to on the weekends.