Prey 2 [http://www.youtube.com/watch?v=WMZva__rU14], by far. It combines FPS action, free roaming, free running, sidequests and a Blade Runner aesthetic. It looks like the game I wanted Star Wars: Bounty Hunter to be, and it's taken over BioShock Infinite as my most anticipated game of 2012.
Edit: there's a longer, better video at Gamespot [http://e3.gamespot.com/video/6318738/].
Edit: there's a longer, better video at Gamespot [http://e3.gamespot.com/video/6318738/].