Not to roll out the Japan bandwagon, but there's a japanese series of voice synthesizers known as Vocaloids, which are programmed using the voices of famous voice actors and singers. Admittedly, they sound like a robot-fetishist's wet dream, but they at least work well enough to have an absurd following in Japan. Of course, almost everything has an absurd following in Japan.
For pronounciation, i figure they'd ask you how it's spoken when you're making the name, so characters could say it as naturally as possible within context. Which i'm sure would be a huge hastle to deal with and still end up clunky, anyhow, so i can understand why they don't do it.
I figure selectable, semi-unique characters would just end up with the Dragon Age system of small details and same damn plot, so i'm not sure how important that would be, either. However, i've got nothing against following a linear story without any real personalization to it, so maybe i'm not the best person to try for solutions on the matter.