When I was a kid, I got mocked daily for reading books all the time and being chubby. When puberty started to kick in, I realized I had few friends, I was socially awkward, and girls were not interested in me. That was a drag. I played the video games, read the "genres" and generally made myself repellent to cool kids and found some solace in that. But the solution to social isolation is not to withdraw into your marginalized hobbies, but to find balance.
By the time I hit high school I decided to turn my situation around. I lost the weight, joined wrestling and got in shape, picked up the guitar, and tried to learn to listen more than I talked. This didn't mean that I stopped enjoying the hobbies I loved--I just balanced them with other more outgoing healthy social activities.
Now, as a college graduate, I don't have to hide my nerdy tendencies or make excuses for my hobbies. They are just one aspect of a well balanced life. Social interaction has to be learned, like anything. It just takes some people more time than others. And, like most things, the only way to get better at it is to practice.