They covered part of that in the Left 4 Dead comic(s).Sniper Team 4 said:The final mission, when you need to cross the bridge, you are on the radio with the military. They start asking if the four characters are carriers or whatever. They respond by saying that they're not infected, and the military stresses that they don't want to know that, they want to know if these people have come in contact with infected and not turned. When the military finds this out, they suddenly become very driven to get those people out of there, but never explain why. To me, this implies that there was supposed to be another game, perhaps one dealing with a chance to find a cure. But all we get is a cutscene of a helicopter taking off and then credits.Ezekiel said:I wonder what you're talking about with the four heroes having interesting stories that needed to be expanded. If there's another L4D, I want it to have an original cast of main characters.
Turns out many of the military units still in operation on the East coast were rounding up the carries so they could use some to find a cure while killing the rest and burning them in mass graves to keep them from spreading the disease to those not immune.
They also explained why so few women seemed to be immune. It was a recessive gene passed down from the father.
It's a fantastic comic well worth the read - http://www.l4d.com/comic/