Yeah, been there, done that, got the stopwatch out. Granted I think this will last longer than some of the shorter term shakeups to the status quo which lasted 2 months, but I'll be shocked if Pete's not back by 2014. We're being trolled by the marketing again, and while it doesn't make this any less stupid, any reader of Marvel for the last 30 years looks at a death and asks "how long do you think this will last?"
Heck, I might be forgiving of this had it been a better villain. Ock's spent a lot of time in a very one dimensional place. He could beat Spidey easily, but has spent too much time on the "I'm crazy so I'll conquer the world" side of villainy for me to see him with any depth. Eddie Brock, Harry Osborne, Norman Osborne, Kaine (reformed now) those might make things interesting. Doc Ock, It's going to be hard to see any new moral view as anything but forced.