Nah. While I find Biowares lack of animation polish and proper voice acting direction repulsive, it is not the reason I won't buy it.
The reason is that despite me liking ME games (even 3, except the ending), I kind of lost passion for them. Maybe it was ME3 ending that did me, or maybe something else, I don't know. Plus, it seems that writing and characters in Andromeda (according to what I've read) are also not very good.
Oh, and the fact that it's on Origin is also off-putting.
And this is sad, because ME is like what, the only big space opera on the market? You just know that EA will simply say "Well, It can't be technical issues, or that most people that made Bioware good have left, it MUST be that people hate Sci-Fi. All Sci-Fi games are canceled".