It's baffling me on how few people talk about how badly they treated Okami through Okamiden. Maybe because hardly anyone played the game long enough to tell, but whatever. They cocked it up badly, and worse than any spelling mistake. It may not be on the box, but some of this was seen in promo material and trailers. It proves that Okamiden was there to cash in on Okami's cult classic status. For example, these three things are fucked up IN THE SAME PROMO CUTSCENE! Here, this is only 1 minute long and you see it all. [http://www.youtube.com/watch?v=JJxU9kZWQoI]
1. Ammy/Shiranui's sex was hinted at being female in the original game. In Japanese, from what I'm told, they don't have gender-specific pronouns (him, her, etc). In this game, they call Shiranui a MALE! REPEATEDLY! According to my friend who plays the Japanese version, it doesn't affect it. Still, that's a terrible translation job when you can't get the sex of a main character in a beloved game right. It's not like "mother to us all" was some cryptic message in the original that was only said once or twice in the 30+ hour epic.
2. Shiranui is Ammy's "past self", so technically they are the same character. The only time they're seen together is when they faff about in the past. Well, it seems like Capcom was asleep during that time and saw that there were two wolves named Shiranui and Ammy. So now in Okamiden, they're treated as different characters *slow clap*. This isn't a translation error by the way.
3. Chibi (the pup in Okamiden) never had his past explained. One of the major plotholes in the game, but something worse happens. Early in the game, Issun assumes Ammy is Chibi's mom...somehow. Now back to Shiranui. Again, this is NOT a translation error. Shiranui claims to be Chibi's GRANDFATHER. Why Shiranui would even know this is beyond me, but MAN! If it was written in betterI could believe Shiranui was Chibi's grandmother (even though the game doesn't hint at all at Shiranui or Ammy having any children). I've heard that they could mean an "incarnation" as opposed to being a sexual "birth", but they could've made that a lot clearer. I mean, Issun at one time (if I remember correctly) wondered who Chibi's father was.
Of course there are the plotholes, the story feeling dead, how little the story is about Chibi, Ammy, Waka, or previously loved characters, and many other continuity issues with the previous games. The picture is the same though. Capcom doesn't care about Okami. Simple. Okamiden is proof. Many fans consider the game to be 100% non-canon.