Sgt. Sykes said:
Mass Effect's Male Shepard. Holy dong, how did they end up picking this guy? FemShep and almost everyone else in ME gives great performance, but the titular male is just terrible.
I felt it was the opposite. ME1 had a bit of a stale performance from MaleShep, but in 2 and 3 he knocked it out of the park. But femshep? Never... really... changed. She was thoroughly boring and tedious to listen to in the first game, and kept that up for the whole series. Her attempts at snarky comments or witty replies fall completely flat, and her angry voice sounds like someone who heard about anger in a five-hour conference with guest speakers and a powerpoint presentation, but never experienced the emotion first-hand. It was very jarring.
After playing through all 3 games as male shep when they came out, I went back a year later to replay them as female shep to do all the DLC content I'd missed, and I had to stop playing midway through 2 - just couldn't stand her voice. Tried to pick her up again with 3, and couldn't do it there either. She just did not sound remotely interested in what was going on, let alone leading every living race in a resistance against killer space robots. Even aside from specific lines that MaleShep just excels at (you big... stupid... jellyfish! etc) the "overall" feel of Shepard was just way better with him. And when he was angry, he was angry; or at least mildly heated. Femshep might as well have been voiced by keanu reaves for all the emotion she displays.