I would like to think this counts. Actually, this is precisely what I came in here to say. To be honest, it's a bit weird having Isaac talk in Golden Sun: The Lost Age. I found it even weirder that Felix somehow lost his voice.Scarim Coral said:Does Gold Sun 1 and 2 counted?
In the first game you played Issac but in 2 you played the other character Felix and his group. When you are reunited with Issac group he can talk since you're not playing as him in 2 so it was quite werid having him being able to talked. Ok this also in turn make Felix one talkable in 1 to being the silent protagonist in 2.
I'd also like to mention Kimahri from Final Fantasy X. He doesn't say a single word until a good way into the game, and his first words are to tell Tidus to keep a positive exterior, for Yuna's sake. Even after that, he still says next to nothing.