I don't like Liara from the entire Mass Effect series.
Following contains spoilers.
In ME1 she made me seriously uncomfortable and she had a serious case of nerd bait personality going on. For ME1, I did the typical thing I do with most games, avoid talking to the character I don't like. I just did not talk to her and did not use her on missions. However, she's important for mind reading/raping Shepard to find clues. If you pick her up early, she does it after every major story mission and feels faint afterwords. Then somehow Kaidan will still think Shepard's trying to hook up with her, even if you've never stepped foot in Liara's room. Stupid game mechanics yes, but still annoying.
In the comic, she really didn't do anything that important. Saving Shepard was reliant on Cerberus and Feron. Feron made the decision to save Shepard after thinking selling Shepard's body was not his thing. He didn't change his mind because of Liara. The events leading to Feron's capture were circumstantial, if Liara didn't spend most of the comic being Bipolar every other page and smacking Feron around, they may have rescued Shepard sooner. Finally, Liara thought it was better to leave Shepard dead.
In ME2 turns out you can't avoid her. You have to talk to her to pick up Thane and Samara, and besides the fact they are two of my favorites, you can't complete the game without Thane or Samara.
In Lair of the Shadow broker, she is creepy as hell, especially if you spent most of ME1 never talking to her, and you find out she's hoarding Shepard's armor and dog tags. It's incredibly stupid that not inviting her over to spend time, she acts super hurt, but in ME3 she seems to forget this completely and loves Shepard again.
Things became a little interesting when she became the Shadow Broker, but it amounts to nothing in ME3. Specialist Traynor gives Shepard more info than Liara does. I have no friggen clue why Liara is the Shadow Broker, what was the point of that plot? What she does important in ME3 is right at the beginning, and it involves her old job as an archeologist. Then she does nothing for the rest of the game but constantly come to Shepards room and add lots of drama on the ship.
There is a point where you invite characters up to Shepard's room, and you have to invite Liara first before you can invite anyone else. You can't skip her, you can't skip anyone, but she is first and you have to invite her up to get to anyone else. Then, you can spend the entire game not talking to her, not taking her on missions, not comforting her, then at the end of the game, she pulls out this random memory mind sharing crap like you're still best friends with her.
So yeah, I really don't like Liara.