As I said in a previous Monster related thread, no, I don't think that Twilight ruined Vampires, nor did the action-horror/survival horror model of vampire story water down the impact of pre-existing stories retroactively anymore than Bozo the clown makes John Wayne Gacy or the Joker look cute and cuddly by association.
Not only does this go for other monster archetypes but any type of fictional trope at all.
It's as if a form of madness is creeping over the internet that causes people to froth at the mouth whenever something violates whatever mindspace territory the favorite authors of their youth claimed for themselves, whether it be related to giant robots, beast people or mystical ninjas, often missing the part about those interpretations themselves being 'bastardizations' of the previous versions of these concepts.
What really is 'killing' the older concepts of vampires is their creeping irrelevance. Badboys out for blood and the self-destructive women who love them have more resonance with teenaged girls and young women than corrupt aristocrats preying upon the lower classes do these days. Don't blame Stephanie Meyer, blame the passage of time and its effect upon modern society and, of course, the fact that nothing has really been done with the vampire concept outside of action movies in a while.
As is the case with nearly everything that becomes passe`, adults re-packaged Vamps and gave them to the youngsters as a gussied-up hand-me-down.
Hmm. Ironically, Old Age maybe be what is 'killing' Vampires.
Maybe if the Vampire is reborn as a crooked politician or the Totally-Not-the-Catholic Catholic Church psuedo-religion(from Count to Cleric?)or terrorists who feed upon terror itself (any of the complainers are free to use any of those ideas for themselves... if I don't use them first!), they'll suddenly become relevant to adult audiences again.