Many A True Nerd is definitely my favorite. He's a British video gamer, who was originally working as a banker, with a classical history degree from university, who found that people really liked watching him do goofy things like runs of Fallout 3 and NV, where he kills everyone, or kills nobody. Then tries to play them without ever dying once, and no healing, (You Only Live Once runs). And other various goofy style gaming. He's got a funny sense of humor, an interesting, analytical look at gaming, and their pros/cons, and is just fun to watch for me. Plus he and I tend to have similar tastes in games, so it's pretty good odds that a game he highlights, and enjoys, will probably end up in my library.
The Atheist Experience. While it's difficult for me to watch the show these days, as it's the same, tired, lame ass type calls from religious types, it's still an informative show/channel.
Tiny Kittens HQ. It's a livestream of rescued cats/kittens, usually pregnant cats from a nearby wild cat shelter. You get to watch kittens growing up, being adorable, and playing. Pretty much everything great about the internet.
The Spffing Brit. He's quite fun to watch totally break games by finding their exploits, and highlighting them in a humorous manner. Even for games I have zero interest in playing, it can be a riot to watch him just jack everything up.
Dominic Noble (aka The Dom). He became known when he first was linked to TTWTG, but has since become his own platform. He does "Lost in Adaptation", where he compares book/movie/tv adaptations, and grades them on how accurate they are/aren't to the source material.
Legal Eagle. Lawyer that reviews law movies/tv, and grades them on legal accuracy in a funny way. Lately he's been becoming more IRL activist due to the crazy shit going on in the US, and how the laws are being flouted in ways that disturb him, but he still is an amusing content provider. His review of My Cousin Vinny is one of my favorites.
Matt Baume. LGBTQ content provider, where he reviews tv shows that touch on the topic of LGBTQ representation/subjects, showing them for what they are. He does it in a funny, yet also sort of a historical timeline manner. He also reviews movies with LGBTQ content as well.
I'm sure there are others, but that's the ones I'm thinking of.