the only plasmid i really ever use is telekinesis, its it uses the least amount of mana )0.o sorry, eve, and does hella damage. the only time i use anything else is when there are no stray cigarettes or stuffed bears to throw at people. i liked freeze too, but that way you cant loot their bodies, plus i always wished you could freeze people, then melt them to a puddle wait till another baddy runs into the puddle of liquid dead bad guy, and electrocute him in it. downloadable content perhaps?
weapons, the crossbow had style, but didn't do enough damage, and felt really slow and awkward. i mostly just use the shotgun. chemical thrower is useless, it doesn't let you do anything you can't do with a plasmid, pistol is too weak and only has 6 shots before taking forever to reload like everything else, but i guess that is realistic. machine gun is good for taking out bots when you trip the security alarm, and there is nothing like taking down a big daddy using nothing but a wrench. great game that i still play. there is my little rant.