Hmm ... see my avatar ..
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Elite II: Frontier. I'd played the first one but never really though about it much. I was old enough to appreciate the incredible work David Braben had done by creating a galaxy that could replicate ours not just with four or five systems, or 50 or 60, or 500 or 600 ... but with, as far as I could see, INFINITE systems. That shit blew my mind. I remember jumping from Sol to Barnard's Star, and trading, and so on, just to see if I could reach the absolute limits of human expansion. Goddamn it took in-game months of travelling.
Once as a kind of weird little Moses homage, I took a ship with a few dozen tons of slaves (lol i love how we counted them in weight, nice and dehumanising), farming equipment, tools, medical supplies, live animals, weaponry, and did a forced 'misjump' (pirates could track your warp signature and calculate your destination point and jump after you, ambushing you when you arrive). Misjumps were a good way to get out of a sticky situation without anyone following you, but they were risky - you could burn out your jump drive rendering your ship an expensive paperweight, or capable of only intra-system or environmental flight. Anyway, my forced misjump did exactly what I'd planned - dumped me in an uninhabited system some 10,000 light years from the edge of human space and burnt out my jump system. There was a suitable planet for supporting life as well - so I flew down, landed on on of the northern continents, and established the Empire of Uzo by freeing my slaves (and keeping it a secret that I'd done it on purpose, of course).
I like to think that we would have been happy on our isolated little alien world a bazillion gazillion miles away.