My Fave is Akia Katana on the 360. I love the phantom mechanic and the use of Katana's in Climax mode. Drop dead 2D visuals to boot.
SkullGirls: First 2D fighter i've played in a long time, love the artstyle and jazz music. The gameplay is just want I want from a 2D fighter, Largely ignored by gamers which is a crying shame because it's a joy to play and one of the best value games on XBLA & PSN
FTL: This game was like crack until I beat it on normal, one of my most enjoyable gaming experiences for a long time.
Binary Domain: Fixes everything that is wrong about Gears of War, ie the pacing, gamefeel, enemies, weapons and bosses (just about everything really)
Ys Origin: The best 2D zelda clone i've ever played, fast pacing, great bosses, no grinding, why can't more games be like this!
Dust, An Elysian Tail: Similar to Odin Sphere and Muramasa. And while Vannilaware is still tops for visuals, Dust has better gameplay for sure.