I hate clunky menu interfaces that are difficult to navigate (and sometimes slow to load). Fable II was terrible for this. Items weren't organized in your inventory. The map was practically useless. Worst of all, if you used an item, the game automatically exits the menus. Oblivion and Fallout 3 were pretty crappy in this regard as well.
I also agree with whoever mentioned time limits.
I also agree with whoever mentioned time limits.