Final Fantasy 1 - Welcome to Corneria!
Final Fantasy 4 - Earth totally has a secret underworld, you guys.
Final Fantasy 5 - Elements are bad, trees are bad, but misreading 'Dawn Warriors' as 'Damn Warriors' is cool.
Final Fantasy 6 - Clowns are evil.
Final Fantasy 7 - The planet is actually bad at its essential job of preserving life balance throughout the world and cannot handle one intruder. Also, genetics is fun!
Final Fantasy 8 - There is no logic or sense to apply to this game, so frankly there's equally no way to properly lampoon it. Let's just go with "Fuck all logic" for the time being.
Final Fantasy 9 - The people of Terra were/are Super Saiyans.
Final Fantasy X - Everybody is completely blind to the obvious evil going on, ergo Spira is doomed.
Gundam francise, Mazinger franchise, Zone of the Enders franchise - Mecha are really easy to pilot! (Macross/Robotech calls bullshit, though.)
Fallout 1 - Dogmeat died for our sins. Also, genetics is fun!
Fallout 2 - The Enclave unwittingly doomed the entire wasteland by destroying their intelligent Deathclaws because they didn't follow orders, never realizing that they still could have pacified all Deathclaws everywhere.
Fallout 3 - Because war never changes, being a dick in the wasteland is the only way to get by because actually trying to do something to fix what's broken around here will have everyone turn on you.
Fallout: New Vegas - Don't fuck with the mail. (That MIGHT be a correct interpretation, actually...)
Fallout 4 - Wow, the Enclave must've had nearly ALL the fusion power of the wasteland to keep those powersuits running all the time!
Persona 1 - Butterflies bring tidings of disaster and psychic power.
Persona 2 - See? I told you! Also, Hitler. Just because.
Persona 2 - You ever get that deja vu feeling?
Persona 3 - The man with the biggest nose in the county and no friends is the best person to listen to about Social Links.
Persona 4 - The MC and the villain are one in the same because Jonny Yong Bosh voiced them both.
Shin Megami Tensei: Nocturne - The Devil made me do it.