Yup. Toonstruck. To elaborate: it's a whacky adventure game, featuring Christopher Lloyd as the main character, a cartoon designer, who gets thrown into the cartoon world of his most successful creation, an epicute bunny thing which he despises. Yeah, I know, sounds crazy, and guess what: it's even more so.
Well, there is a scene where you have to get a new costume for the Carecrow. Nice fella, and the puzzles are quite challenging. Well, you give the costume to him, he gets totally happy, sheds a tear and BAZINGA! in comes the local evil overlord and zaps him with his ray gun that turns everything into a very evil, twisted version of itself.
It was heartbreaking for me. See it here: http://www.youtube.com/watch?v=-TExni9SiIg