Even if I don't like his games very much (or him for that matter), the man has a point.
The idea of sequels isn't all that good. Make it good, and get it right the first time. Without sequels, every story has to be fresh and interesting. This doesn't exclude the autor from the ability to make something in the same universe, but it gives us stories with some actual closure for once.
Also, actually having something driven by a single person should make for a much more coherent experience (except if it's Suda51...) than what we have now - plot holes the size of Uranus alongside reality rifts the size of Jupiter.
Video game storytelling is too much oriented to be like a movie. And, let's face it, neither game storytelling from the ME school nor storytelling from the David Cage school of videogame storytelling is going to do much to help. Though maybe he has plans to move in the right direction, who knows.
There is a kind of story you can only build in a videogame. A kind of story where every choice has meaning and the player decides in which direction it goes. The problem with doing something like this is that either it's going to feel awfully limited because of limited resources or it's going to take literally forever to make. A directed story is easier to make, and it's easier to balance gameplay along the way.
Hmmm... normally tedious things in games are included to provide a heavier contrast when things go downhill. It has to be balanced properly though. And that (amongst other things like gameplay) is something the guy needs to learn. I remember a quest in Two Worlds (I got it after all the issues had been patched
) where you basically ferried a few packages around for the traders' guild until they noticed you getting suspicious (which was about 3 trips in - mind you,there was fast travel in the form of portals outside every major city in that game), after which they flat out admitted that they had done that just to see if you're any good. Actually, that's one of the little fetch quests I remember where the creators actually put some thought in - it made sense in the game and the traders' guild doesn't just trust you from the moment you show up on the doorstep of their dependance. I'm going off topic now, so I'd better stop.