Cap said:
Tie him down with some nice strong chains that stay out of the way of his claws, then hand him over to a crematorium and get them to cook him at gas mark 50 for 36 hours, then before he has a chance to regenerate any ligaments or tendons, separate the adamantium-coated bones and encase them in concrete.
Wolverine survived the equivalent of a nuke blast, and regenerated from nothing but a skeleton. I don't think that'll work...
http://media.comicvine.com/uploads/4/43469/871457-wolverine43_017_018_super.jpg
http://media.animevice.com/uploads/0/3388/275264-wolverine48_012_super.jpg[/quote
Aye, I've seen those pictures, and took them into consideration in my answer.
He can't heal during sustained damage i.e. the constant heat of being cremated and then you separate the bones once all of the tissue is gone. If the bones aren't together, he can't create new tendons and ligaments, and he can't regenerate more adamantium as that isn't a part of his natural physiology so he can't regrown from one bone. By encasing the bones in separate blocks of concrete, that means it's even harder for the bones to get close enough together for him to recreate himself. Even if his jawbone or something broke out of its block with the flesh regrown around it, it has no means of propulsion because it's just a jawbone and isn't attached to anything else.