Honestly, the only times I get bothered by a lack of female main characters is when part of a games appeal is character customization. For example: Battlefield heroes. I was surprisingly annoyed by the sausage fest.
In other examples, Deus Ex: Human Revolution and Assassins creed 2. Never bothered by those, probably because the main characters were pretty hawt.
In a proper PC-RPG I'd rather have a female option. Especially if I can customize her to my tastes. Generally speaking, there is little reason to not have a female option available apart from the game being focused on a specific character such as in... Uhm... I can't seem to be able to find any good examples, in particular after playing Bioware games.
In other examples, Deus Ex: Human Revolution and Assassins creed 2. Never bothered by those, probably because the main characters were pretty hawt.
In a proper PC-RPG I'd rather have a female option. Especially if I can customize her to my tastes. Generally speaking, there is little reason to not have a female option available apart from the game being focused on a specific character such as in... Uhm... I can't seem to be able to find any good examples, in particular after playing Bioware games.