Now it's personal.... - Your versions...

[Zenoxio]

Phantasia 4 is a text-based online game that I used to frequent often a few years back. It borrows a lot from Lord of the Rings and Dungeons and Dragons. During one playthrough, I accidentally ran into Saruman, an evil wizard from LotR. I fought him intensely and eventually won but not before he cast a spell that, to paraphrase, "made me feel different somehow." I checked my stats and found a bombshell: he changed my freaking gender! I vowed then and there to obliterate Saruman in the most humiliating way possible every time I faced him, no matter which game.

Oh yeah, it's personal.

Phantasia 4 just came back recently I think: http://en.wikipedia.org/wiki/Phantasia_(video_game)

 

[Captain Pirate]

In Bioshock when... well, when the twist happens. So I don't spoil it for anyone who hasn't played the game (You damn well should), all I'll say is, that I felt like it was me, not the guy I was playing as, who had been manipulated.

Also, in Black Ops when <spoiler= SPOILAARS> Dragovich, Steiner, and Kravchenko kill Dimitri (You) for a worthless reason. I'm with Reznov, he should've died in Berlin like a hero.
And when that Russian POW Camp commander forces you to play Russian Roulette with Bowman, and when you and him refuse, he smashes Bowman's head in. Most satisfying enemy kill in all of Call of Duty is when you chase him down, and as the fucking coward tries to open a hatch door, I emtpied the whole damn AK mag into him.
The fucking prick. [/spoiler]

 

[pyrosaw]

I was doing the superhuman gambit in F3, then the ants killed Dogmeat. Shit just got personal.

 

[Fallen-Angel Risen-Demon]

Pokemon Mystery Dungeon: Explorers of Sky/Time/Darkness

Spoiler

NOOOOOOOOOOOOOOOOOOOO!
GROVYLE!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

 

[Goombuster]

Fable 2. Lucien, you son of a *****. You shoot my sister, you kill my dog, YOUR ASS IS GRASS AND I'M GONNA SMOKE IT.

Seconded. When he shot my dog things got real.