I am very much pro twitter - let me explain why.
I use it to get a glimpse into the lives of others as well as receive the news is short bites. I'm subscribed to several news feeds like The Guardian and some geek ones. I follow Stephen Fry, Will Wheaton, Adam Savage, Drew Carey, David Hewlett, some random porn stars cause I was curious about their lives, a theoretical physicist, a guy who runs an oil rig on the Atlantic, a Hindi match maker and a young gentleman preparing for his first trip into space as an astronaut.
Why? Cause all these people have lives that interest me. Granted, the average joe is not going to have an exciting stream but I use it to take glimpses into the lives of people that do interest me. My feed isn't have as cool as these people, I am generally just retweeting their stuff to my friends or sharing fun links / strange observations.
It's a great way to keep up with the news in your area (Via the trends) and to take glimpses into lives a little different than your own. Following people who tweet what they had for breakfast every day is no fun, but try to think outside the box. Wefollow is a website which promotes popular and interesting twitter users based on category.
Check it out!