Actually there were a few games set in the Midwest so pretty much the whole of America has been somewhat taken into account, east, midwest and west. I think that the European angel could only work if it was in the pre-war era (Although that might be where MW3 is heading heh) Or it would have to be in England, possibily with a bunch of American tourists with more of a survival maybe Dead Money sort of feel. I really would like to see an apocolypse game FEEL like an apocolypse game and not one that makes you feel safe because you have a suit of power armor and a gun that shoots metal death. And Asia could only work in China mabye as a US soldiers right after the Great War or a little after working with a number of other American survivors, Shi Empire style from Fallout 1 (or mabye it was 2 I dont remember0