I'm going with KotOR 3 and Jedi Knight 3 (or 4, if you consider Academy a real sequel, which I don't).
SWTOR is definitely on my to-buy list (at least for the time being), but it won't replace a proper KotOR 3.
As for Jedi Knight, it's one of the best Star Wars series they made. Right up there with KotOR. Unfortunately, the steaming pile of dung that was Force Unleashed seems to have taken JK's spot.
Also, Warcraft IV. It sure as hell won't happen anytime soon, but I hope they'll get around making one eventually. The Warcraft games are by far my favourite RTS (yes, even more than Starcraft).