Actually, what we're talking about here is mostly the proportion of male to female voice actors employed in the making of the game. The Asari may _sound_ like women, and they look like escapees from one of George Lucas' teenage wet dreams, but the game makes the point that they are all asexual (and as they apparently have sex by thinking hard at your genes, I have trouble understanding how they even get their reputation for sensuality - the human way sounds like heaps more fun.) The only Quarian I've met so far looks and sounds female... through a full facial helmet that never comes off - who knows whats under there? The Salarians, Turians, Krogan etc. all sound male, but I'm not sure I'd even go so far as to say they look it. Turians look like bipedal grasshoppers; whats a female grasshopper look like?
Any use of human pronouns to describe aliens is bound to be inaccurate, but walking around calling everyone "it" is distancing and distracting. Given that the humans were going to arbitrarily assign them sexes, can you blame them for using the one that matches the perfectly accented American English coming out of their mouths? The Elcor and the jellyfish-dudes were the only things in the game that felt properly alien.
That said, Anaphyis is right; most of the rest of it I can deal with, but the all-Asari pole-dancers is just dumb.