I am a highly irritable person, and so I have many single lines that make me see red. A small cross-section that spring to mind:
"Ahh got somethin' for ya" - Borderlands
"I'm gonna shoot you in the face" - Far Cry
"OOO check me out IM DANCIN, IM DAAANCIN" - Borderlands
"Get out of here, stalker" - STALKER - Shadow of Chernobyl
"Hello, Hello" STALKER - SoC
"My information may be of use to you" - STALKER SoC
Hmm STALKER is highly represented there. Its kind of notorious for looping the most annoying dialogue. Great game though.