I also recommend you reformat your main drive, viri are a ***** to get off windows, expecially if you arent technically oriented.
Id boot into safe mode, transfer all your files off the main drive that you want to save.
You CAN use the windows disk to reformat the drive, dont select the repair option and it should delete the partition and reinstall.
Before you proceed make sure that you dont have ANY files that are encrypted, reformatting the drive will erase your encryption key and its dam near impossible to unencrypt them.
Also make sure you have a way to get your drivers reinstalled, specifically your motherboard drivers. Make sure you have your windows key.
Alternatively, if you arent comfortable with safe mode, you can try to kill the processes that are running the viri. I would just ctrl-alt delete and "end process tree" on explorer.exe. That will kill explorer the main shell windows uses AS WELL as any processes started by it which tend to be the viri. Then just "new task" and type explorer.exe. That should kill the viri that are started on startup. This is just a temporary way to get your computer to run well enough to get the files off it.
Honestly though, I'd just transfer all files, reformat your main drive and then make sure everything is updated to prevent the virus exploting loopholes. I am also giving "AVAST" a try as its free and it hasnt pissed me off nearly as much as other anti virus tools, it just prevents viri not removes them.
Dont use internet explorer, keep your software up to date, have a firewall, Or just run linux. Be careful updating windows though as it installs "Verification" software that might as well be a virus. If you are using pirated programs it will be a pain in the ass, although you can crack it.