Trying to avoid spoilers.

[Amethyst Wind]

I downloaded the Da Vinci Disappearance DLC for Assassin's Creed: Brotherhood.

A question for those who have played it. Chronologically, when does the story take place? Is it to be played after completing the main quest or can it be done at any time?

I'd rather avoid doing it until the end if it spoils parts of the main quest.

 

[Supernova1138]

I believe the Da Vinci disappearance DLC takes place just before the game's final chapter. I got Brotherhood on PC and it included that DLC right out of the box, it automatically played between the second last chapter, and the final sequence.