No games in my 360, due to me watching Firefly then lending it to a friend, but the last one I played was Oblivion, and the last disc in there was Firefly: The Complete series disc 1.
And in my DS, Final Fantasy III.
And in my PC, no discs due to me buying most of my games on Steam, and the others being no-disc-needed, but last played was Team Fortress 2.