Fruits Basket. But I suspect you didn't want a manga for an answer, no matter how much it counts.
In that case...Blackest Night. After false starts with Transmetropolitan and Watchmen, and a general lack of interest in superhero comics, that one has so far managed to be a shining, anomalous exception.
Then again, I'm also a sucker for color coding, so finding out about the other lantern corps (especially the Red Lanterns) drew me in instantly.
And I just love saying "Ruffles the Rage Kitty" over and over.