Let's see here...
The Doctor (Doctor Who): would just trap him in an event horizon, shackle him in chains forged in the heart of a dwarf star, just push him into the time vortex or just leave him at the end of time.
Batman (DC): Give him 5 minutes and he can beat ANYONE.
Superman (DC): Even post-crisis Supes could take him.
The Sentry (Marvel): Just like Supes but crazy.
Locke (FF6): Equip the Atma Weapon and the Valiant Knife, Genji Gloves and Offering. Quick, attack, attack. Dead.
Citan Uzuki (Xenogears): The fact that he is more powerful outside of his gear than inside of it speaks worlds about how broken he is.
Thousands more....