Let's be honest. What would you do if you had superpowers? Devote yourself to taking small time criminals off the street late every night and early every morning while also saving cats and donating to charity, or fuck around and destroy shit? "With great power comes great responsibilty." Unless he's talking about political power that's complete bullshit. Spiderman could have easily just used his powers to jump around and off of buildings all day or to take the mayor hostage. It's just that his personality didn't allow for it or something. The only motivation for not going on a killing spree being that he'd be killing unique, innocent individuals. With that gone, there's even less motivation to spare people in sandbox games because you know you're going to kill a pedestrian only for his clone to walk around the corner and get killed again. Who the hell wants to be responsible for their actions unless it's actually relevant to the story (screw the RDR honor system, i'm going to say that right now)? As for why we cheer for villains, it's because they have an excuse to be an unlikeable douche. However, more and more things have made the hero extremely unlikeable, sometimes to the point where you just want the bad guy to kill him already so you don't have to hear another line out of his smug prick mouth.