i usually like to go with the A3-21 plasma rifle, because it can be found early in the game, and its degrade is reasonable, not to quick to break down, but when it does start to its annoying to fix, under that i always go with either Ol' Painless, or Vengeance, both are amazing, Ol' Painless is one of the easiest weapons to repair and get ammo for, and vengeance is just an amazing weapon, also if i'm in a glitch abusing kind of mood, the original (no DLC) Col. Autumn's Laser Pistol is fun to mess around with