Since the game was written by a Deadpool writer, I think the story is fairly on par with the comics.
Overall though, the gameplay was just alright. I particularly wasn't a fan of the shooting sections, and there are certain enemies you have to shoot, but you run out of ammo...then you're kinda screwed.
Also for a game full of chest high walls, you'd think we'd be able to crouch (and if we can, I'm pretty much through the game with no idea how to do that...)
But yeah, it's Deadpool at his Deadpooliest with decent melee combat, slightly below average shooter combat, and really what I think determines if you'll enjoy it or not really is just based on how much you enjoy Deadpool as a character.