Have you seen a zero punctuation episode before?Psykoma said:"No trannies"
hm?
If not, did you notice the incredibly tasteless holocaust joke in the middle of this episode?
Sometimes, in comedy, people say things which are crass, insensitive or unpleasant. Sometimes, they do this because they are actually serious, or because they're trying to appeal to people who are actually racist, homophobic, transphobic, misogynistic or otherwise unpleasant. There is such a thing as "laughing through bared teeth". Such comics don't tend to get very far nowadays because they aren't funny, racists/homophobes/misogynists/etc simply pretend that they're funny as a political act.
Other times, people make offensive statements ironically as a way of breaking social taboos for comedic effect. This works precisely because the audience would not admit to being racist, homophobic, transphobic etc and will thus find the statement shocking or unexpected. If this were not true, the joke would not be funny, it would be just as shitty a joke as the above.
I'm not saying such comedy can never be offensive. Yahtzee has certainly said a couple of things over the years which I personally found to be in quite poor taste, but generally speaking the irony is quite thick.
The true test of comedy, for me, is whether it translates into actual hatred, bullying or belittling, and the only people I've ever seen get actually harassed over anything Yahtzee has said are CoD fans.