I hope you're not planning to drink two handles of vodka by yourself all at once? Or if you are, I hope you have all your affairs in order. Anyway, some of my recommendations:
Screwdriver - Very simple, and my personal favorite. Simply mix your desired amount of vodka with orange juice.
The McLovin - AKA The Hawaiian Knockout. Mix roughly three shots of vodka, two shots of Smirnoff Ice (The regular lemonade flavored one) and fill the rest of the glass with Hawaiian Punch. It sounds weird, but it's amazing.
Twiztid Tea - Mix your desired amount of vodka with equal parts of iced tea and lemonade.
This last one is a bit different and requires preparation:
Vodka Cherries - Buy one of those cans of cherries (Not fresh ones, the canned ones are sweeter since they soak in the juice) drain the juice and place the cherries in a jar or other container. Fill the rest of the container with vodka and seal it. Leave that for about a week, then eat the cherries. They'll get you drunk.
I have one more, but it requires some illegal ingredients and I've decided not to list it here.