I will not say anything about actual gameplay, because I have not played the game or demo.
But I am currently watching a playthrough of it, so here is what I think about other aspects:
Graphics: looks nice, but playing vidiagamez for graphic is like watching porn for a story.
Aestetics: also nice, but too many acid colours, which hurt my eyes.
Music: not really liking it. While in previous instalments music had suiting rhythm, this one does not, which hurts the flow.
Presentation: Clusterf*$k. Opening sequence did it to me. You may make main character a womanizer or an innocent sheep, gentle lover or lust hungry beast, but you do NOT start any game, movie, whatever, with shots of female reproductive organs and two females making out. Class people. Class!
Main character: I can't say that I REALLY dislike him, he may be as rebellious as devs want, it is their right (too much swearings, though). But what I DO find revolting is NT's treatment of heritage. Example: during one of the cutscenes, a white wig lands on Dantes head. He looks in the mirror and says: "Not in the million years". That is just a big Screw You aimed at fans of the series. No matter how much potential client, potential buyer annoys you, you always treat him/her with respect if you want your stuff to be bought. Also, why couldn't they simply change his name to, for example, Caesar? The whole controversy would have been avoided. Imagine, that if you like, for example Stree Fighter series, it gets rebooted and suddenly Ryu is a brash, cocky street punk, who learned his skills from his father. Now it doesn't sound to horrible, but imagine if it really happened. But change his name to, for example, Shiro, and negative reaction is soothed.
Minor: I like how guns shoot, I dislike that gaining SSS rank is a lot easier.
OK, here is something to lighten up the mood: