Nope, not via public face to face interactions, as I adopt an extremely inoffensive and unobtrusive public persona - people who only know me through our interactions in public think I'm an extremely quiet person, and I either get along with everyone or they simply do not notice me at all. A woman who had known me for years found it rather puzzling when my family just busted out laughing when she commented on just how quiet a person I am, since she'd only ever seen me through the medium of the shared social setting that precipitated our interactions.
Now conversations with family members or those few individuals who I favor with a glimpse of my real personality (to say I am an opinionated firebrand who adores arguing for its own sake would be understating it a bit), there I don't need to "think" I've pissed them off, as I absolutely will, no question about it (provided we ever disagree about anything, heh). Likewise, I will frequently post things that I'm absolutely certain will provoke angry reactions from other people - not so much because I want to make them angry mind you, I just don't feel the need to get along with anyone espousing the opposite stance on issues I take an ideological stance on.
With all that said, I'm still a genuinely much nicer person online than in person, in that I have a habit of going out of my way to help people (sometimes with subtle mockery, but helping nonetheless!), whereas I'd probably just ignore those same sorts of queries and issues if they were raised by strangers out here in meatspace.