We'll probably have less hair. Our bodies will probably be more frail. We might develop weaker immune systems. Not sure if we'll start developing lighter skin or not. I can hope that our mind will become "stronger" but I can't be too sure. I mean sure there are lots of stupid people out there, but I bet that they're smarter than some of average people several hundreds years ago.
Why do I guess these changes? Because our lifestyle doesn't require us to be very strong or fast or enduring. We can drive down anywhere we need to go, we simply buy food in stores, and our ability to create small controllable environments (or at least put on clothes) means that we don't have to endure nature 24/7. So naturally weaker bodies have just as much of a chance to survive as hardier bodies. Hopefully our need to use our minds more will help to make the more mentally strong (and I don't mean knowledgeable, I mean those whose minds can "work" harder) be more successful and thus propagate more, but I don't know for sure.