Most of my gripes about the game are technical in nature. The fact I had to adjust a bunch of config files before the game was in a playable state for me because of low FOV, mouse smoothing, mouse acceleration, and a few other things. It also has a god awful UI for a PC game, which I am mostly used to by now for most games. It just bugs me because if Larian Studios can make a totally unique UI for console and another one for PC, with their 30 cent budget. Why can't Bethesda? Answer, laziness.
The game also seems to be way cut down on RPG aspects, and more of an action shooter. Good basis for modding though. I am sure the game will be much improved once the community starts working on it. Which isn't really a positive for Bethesda in my book.
That said, it is about what I expected. Its fun, with a ton of problems and lots of missed opportunity. A bit like Skyrim was. I'll enjoy it.
But seriously, fuck the UI.