Oh, and this as well:
[hr]
Harbinger: Human, you've changed nothing. Your species has attracted the attention of those infinitely your greater. That which you know as Reapers are your salvation through destruction.
Harbinger: *turns to Collector General* You have failed. We will find another way. Releasing control.
Collector General: *looks around in confusion and sadness, possibly for the first time in its life, as fire immolates the entire room*
[hr]
Practically rivals Sovereign's 'you exist because we allow it' speeech from ME 1.
That, and the entirety of the Garrus romance sidequest. Heartwarming, but in a sad way.